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cell based drug screening assays  (TargetMol)


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    TargetMol cell based drug screening assays
    Cell Based Drug Screening Assays, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 19 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/cell+based+drug+screening+assays/Hematopoietic+Toxicity+Compound+Library/pmc07809345__41408_2020_402_MOESM1_ESM-12-13-39
    Average 94 stars, based on 19 article reviews
    cell based drug screening assays - by Bioz Stars, 2026-09
    94/100 stars

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    Drug discovery:

    Article Title: MCL-1 dependency as a novel vulnerability for aggressive B cell lymphomas
    Article Snippet: Antibodies For western blotting, the following antibodies were used: c-PARP (Cell Signaling Technologies, 5625), BCL-2 (Cell Signaling Technologies, 2872), BIM (Cell Signaling Technologies, 2933), BCL-XL (Cell Signaling Technologies, 2762), p-ERK1/2 (Cell Signaling Technologies, 9101), ERK1/2 (Cell Signaling Technologies, 9102), MCL-1 (Santa Cruz Biotechnology, sc-819) and Actin (Santa Cruz Biotechnology, sc47778HRP). .. Small Molecule Inhibitors The following kinase inhibitors were used in drug screening and cell-based drug screening assays: A-1331852 (Selleckchem, S7801), ABT-199 (Selleckchem, S8048), ABT-263 (Selleckchem, S1001), AZD4573 (Selleckchem, S8719), AZD5991 (Selleckchem, S8643), AZD7762 (Selleckchem, S1532), AZD8055 (Selleckchem, S1555), Bendamustine (TargetMol, T0095), Bortezomib (Selleckchem, S1013), Carfilzomib (Selleckchem, S2853), CPA7 (DC Chemicals, DC12009), Dinaciclib (Selleckchem, S2768), Doxorubicin (Selleckchem, S1208), Ibrutinib (Selleckchem, S2680), INCB054329 (Incyte Corporation, Wilmington, DE), INCB052793 (Incyte Corporation, Wilmington, DE), Lumpib (Selleckchem, S1069), NVP-2 (MedChemExpress, HY-12214A), Olaparib (Selleckchem, S1060), R406 (Selleckchem, S2194), Ruxolitinib (Selleckchem, S1378), S63845 (ApexBio, A8737), SCH772984 (Selleckchem, S7101), SR-4835 (Moffitt Cancer Center Derek Duckett Lab), THZ1 S8007), Volasertib (Selleckchem, S2235). .. Methods Generation of S63845 Resistant Cell Lines To establish the S63845 resistant cell lines, MCL and DLBCL cells (HBL-2, Mino, Maver-1, SUDHL-16, and MCL-0448) were grown in RPMI-1640 medium with 10% FBS and treated with vehicle control or escalating doses of S63845 for approximately 3 months.



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